Biology Genetics 

Most of the Human Genome Isn’t Being Actively Studied

By Katherine Lindemann Career incentives drive researchers away from understudied genes that could be important to human health. There are around 20,000 human protein-coding genes, but recent studies have suggested scientists actively study only about 2,000 of them. New research investigates why some genes are studied over and over again, while others are neglected. Its authors found that a genes’ medical significance—how likely it is they play a role in human disease—doesn’t explain the discrepancy. Instead, while many researchers are interested in understudied genes, career incentives encourage scientists to focus on genes…

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